Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.66 |
| ▸ | MGLL | Q99685 | 4/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20567304 | 0.91 | FAAH (0.79) | FAAHMGLL | |
| SCHEMBL20567020 | 0.90 | FAAH (0.66) | FAAHMGLLPHGDHL3MBTL1 | |
| SCHEMBL20567609 | 0.89 | FAAH (0.62) | FAAHMGLLPHGDHL3MBTL1 | |
| SCHEMBL25829854 | 0.88 | FAAH (0.84) | FAAHMGLL | |
| SCHEMBL25829873 | 0.88 | FAAH (0.64) | FAAHMGLL | |
| SCHEMBL25829862 | 0.87 | FAAH (0.61) | FAAHMGLL | |
| SCHEMBL25829980 | 0.87 | FAAH (0.54) | FAAHMGLL | |
| SCHEMBL25830019 | 0.81 | FAAH (0.65) | FAAHMGLL | |
| SCHEMBL25830033 | 0.80 | FAAH (0.64) | FAAHMGLL | |
| SCHEMBL20567176 | 0.79 | FAAH (1.00) | FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630744-B1 | PYRAZOLE MAGL INHIBITORS | H LUNDBECK AS (DK) | 2023-01-25 | — | — | EP | disclosed |