⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14670893 | 0.80 | CYP2D6 (0.30) | — | |
| SCHEMBL25505988 | 0.78 | — | — | |
| SCHEMBL14670996 | 0.78 | HRH3 (0.31) | — | |
| SCHEMBL25471173 | 0.77 | OPRM1 (0.31) | — | |
| SCHEMBL25466558 | 0.77 | — | — | |
| SCHEMBL23515863 | 0.75 | TSHR (0.33) | — | |
| SCHEMBL18125642 | 0.75 | — | — | |
| SCHEMBL21911789 | 0.75 | KDM4E (0.32) | — | |
| SCHEMBL22301801 | 0.74 | CYP2D6 (0.40) | — | |
| SCHEMBL23823374 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220134-A1 | PYRAZINE DERIVATIVES AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023141300-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-07-27 | — | — | WO | disclosed |
| US-20230023009-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | SPARCBIO LLC | 2023-01-26 | — | — | US | disclosed |