SCHEMBL24970972

SCHEMBL24970972

O=C(NCc1ccc(Cl)cc1)c1cnc(N2CCNCC2)c(Cl)c1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CXCR3 P49682 17/20 0.63
P2RY12 Q9H244 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31142964 1.00 CXCR3 (0.63) CXCR3P2RY12
Hydrochloric Acid SCHEMBL30903328 0.99 CXCR3 (0.62) CXCR3P2RY12
SCHEMBL31142862 0.80 P2RY12 (0.54) P2RY12
SCHEMBL24969928 0.80 P2RY12 (0.54) P2RY12
SCHEMBL31142937 0.80 SMN1; SMN2 (0.68) CXCR3P2RY12
SCHEMBL13205805 0.80 CXCR3 (0.93) CXCR3
Hydrochloric Acid SCHEMBL30223058 0.80 P2RY12 (0.53) P2RY12
SCHEMBL1330724 0.79 CXCR3 (0.53) CXCR3
SCHEMBL2417886 0.79 CXCR3 (0.54) CXCR3P2RY12
SCHEMBL24970199 0.79 P2RY12 (0.52) P2RY12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023002011-A1 GRAM-NEGATIVE BACTERIA EFFLUX PUMP INHIBITORS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2023-01-26 WO disclosed