Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 1/20 | 0.45 |
| ▸ | GNB1 | P62873 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10145566 | 0.92 | CYP3A4 (0.46) | GNG2GNB1CYP3A4MEN1KMT2A | |
| SCHEMBL31063708 | 0.88 | CYP3A4 (0.49) | GNG2GNB1CYP3A4MEN1KMT2A | |
| SCHEMBL10145674 | 0.83 | CYP3A4 (0.41) | GNG2GNB1CYP3A4MEN1KMT2A | |
| SCHEMBL28503884 | 0.82 | CYP3A4 (0.62) | GNG2GNB1CYP3A4MEN1KMT2A | |
| SCHEMBL31110328 | 0.79 | MAPT (0.69) | GNG2GNB1CYP3A4MEN1KMT2A | |
| SCHEMBL30320750 | 0.78 | CYP3A4 (0.45) | GNG2GNB1CYP3A4MEN1KMT2A | |
| SCHEMBL18493236 | 0.78 | CYP3A4 (0.45) | GNG2GNB1CYP3A4MEN1KMT2A | |
| SCHEMBL30639273 | 0.77 | MEN1 (0.50) | CYP3A4MEN1KMT2AMAPTLMNA | |
| SCHEMBL26133692 | 0.77 | MEN1 (0.50) | CYP3A4MEN1KMT2AMAPTLMNA | |
| SCHEMBL20436815 | 0.77 | CYP3A4 (0.58) | GNG2GNB1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004400-A1 | DIBENZOXANTHENE QUENCHERS, USES, AND METHODS OF PREPARATION | Life Technologies Corporation (US) | 2023-01-26 | — | — | WO | disclosed |