Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.47 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24972973 | 0.96 | HDAC1 (0.53) | HDAC1HDAC3HDAC2P4HTMKCNH2 | |
| SCHEMBL14885264 | 0.82 | HDAC1 (0.58) | HDAC1HDAC3HDAC2P4HTMNCOR2 | |
| SCHEMBL32662656 | 0.77 | HDAC1 (0.63) | HDAC1HDAC3HDAC2P4HTMNCOR2 | |
| SCHEMBL16209714 | 0.76 | KCNMA1 (0.51) | HDAC1P4HTMMEN1AHRKMT2A | |
| SCHEMBL1063809 | 0.76 | HDAC1 (0.65) | HDAC1HDAC3HDAC2P4HTMNCOR2 | |
| SCHEMBL16209413 | 0.74 | KCNMA1 (0.52) | HDAC1HDAC3HDAC2P4HTMNCOR2 | |
| SCHEMBL1233691 | 0.74 | HDAC1 (0.68) | HDAC1HDAC3HDAC2NCOR2NCOR1 | |
| SCHEMBL32662752 | 0.74 | HDAC1 (0.59) | HDAC1HDAC3HDAC2NCOR2NCOR1 | |
| SCHEMBL25161246 | 0.74 | HDAC2 (0.57) | HDAC1HDAC3HDAC2KCNH2NCOR2 | |
| SCHEMBL16209910 | 0.73 | CXCR2 (0.51) | HDAC1HDAC3HDAC2P4HTMNCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023003468-A1 | NOVEL INHIBITORS OF HISTONE DEACETYLASE (HDAC), AND METHODS, COMPOSITIONS AND USES RELATED THERETO. | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2023-01-26 | — | — | WO | disclosed |