Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.73 |
| ▸ | USP2 | O75604 | 3/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.73 |
| ▸ | RECQL | P46063 | 2/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | EGFR | P00533 | 1/20 | 0.73 |
| ▸ | LCK | P06239 | 1/20 | 0.73 |
| ▸ | FYN | P06241 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | HTR2A | P28223 | 1/20 | 0.73 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.73 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455224 | 1.00 | SLC7A5 (0.73) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| SCHEMBL455225 | 1.00 | SLC7A5 (0.73) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| SCHEMBL30552213 | 1.00 | SLC7A5 (0.73) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| SCHEMBL29393527 | 1.00 | SLC7A5 (0.73) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL23574497 | 0.98 | SLC7A5 (0.71) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL23574498 | 0.98 | SLC7A5 (0.71) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| SCHEMBL5297391 | 0.86 | SLC7A5 (0.62) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| Levodopa SCHEMBL116907 | 0.84 | SLC7A5 (1.00) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| Levodopa SCHEMBL20582239 | 0.84 | SLC7A5 (1.00) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| Levodopa SCHEMBL11000382 | 0.84 | SLC7A5 (1.00) | SLC7A5USP2PTGS1KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4799820-B2 | — | — | 2011-10-26 | — | — | JP | claimed |
| CN-102133407-A | Conjugates of therapeutic or cytotoxic agents and biologically active peptides | UNIV TULANE | 2011-07-27 | — | — | CN | claimed |
| US-7771727-B2 | Conjugates of therapeutic or cytotoxic agents and biologically active peptides | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2010-08-10 | — | — | US | claimed |
| EP-1487493-B1 | CONJUGATES OF CYTOTOXIC AGENTS AND BIOLOGICALLY ACTIVE PEPTIDES | UNIV TULANE (US) | 2010-01-20 | — | — | EP | claimed |
| US-20090324620-A1 | CONJUGATES OF THERAPEUTIC OR CYTOTOXIC AGENTS AND BIOLOGICALLY ACTIVE PEPTIDES | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2009-12-31 | — | — | US | claimed |
| EP-1435826-A4 | DIAGNOSTIC OR THERAPEUTIC SOMATOSTATIN OR BOMBESIN ANALOG CONJUGATES AND USES THEREOF | UNIV TULANE (US) | 2009-07-15 | — | — | EP | claimed |
| EP-1487493-A4 | CONJUGATES OF THERAPEUTIC OR CYTOTOXIC AGENTS AND BIOLOGICALLY ACTIVE PEPTIDES | UNIV TULANE (US) | 2006-08-30 | — | — | EP | claimed |
| US-20060009622-A1 | Conjugates of therapeutic or cytotoxic agents and biologically active peptides | ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | 2006-01-12 | — | — | US | claimed |
| CN-1649625-A | Conjugates of therapeutic or cytotoxic agents and biologically active peptides | UNIV TULANE (US) | 2005-08-03 | — | — | CN | claimed |
| US-20050070470-A1 | Diagnostic or therapeutic somatostatin or bombesin analog conjugates and uses thereof | ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | 2005-03-31 | — | — | US | claimed |
| CN-1589151-A | Diagnostic or therapeutic somatostatin or bombesin analog linkers and uses thereof | UNIV TULANE (US) | 2005-03-02 | — | — | CN | claimed |
| JP-2005505580-A | — | — | 2005-02-24 | — | — | JP | claimed |
| EP-1487493-A2 | CONJUGATES OF THERAPEUTIC OR CYTOTOXIC AGENTS AND BIOLOGICALLY ACTIVE PEPTIDES | The Administrators of The Tulane Educational Fund (US) | 2004-12-22 | — | — | EP | claimed |
| EP-1435826-A2 | DIAGNOSTIC OR THERAPEUTIC SOMATOSTATIN OR BOMBESIN ANALOG CONJUGATES AND USES THEREOF | The Administrators of The Tulane Educational Fund (US) | 2004-07-14 | — | — | EP | claimed |
| WO-2003074551-A2 | CONJUGATES OF THERAPEUTIC OR CYTOTOXIC AGENTS AND BIOLOGICALLY ACTIVE PEPTIDES | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2003-09-12 | — | — | WO | claimed |
| WO-2003028527-A2 | DIAGNOSTIC OR THERAPEUTIC SOMATOSTATIN OR BOMBESIN ANALOG CONJUGATES AND USES THEREOF | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2003-04-10 | — | — | WO | claimed |
| CN-102133407-A | Conjugates of therapeutic or cytotoxic agents and biologically active peptides | UNIV TULANE | 2011-07-27 | — | — | CN | disclosed |
| US-7771727-B2 | Conjugates of therapeutic or cytotoxic agents and biologically active peptides | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2010-08-10 | — | — | US | disclosed |
| EP-0850316-A1 | CRYPTOPHYCINS FROM ABERRANT BIOSYNTHESIS | UNIVERSITY OF HAWAII (US) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997008334-A1 | CRYPTOPHYCINS FROM ABERRANT BIOSYNTHESIS | UNIVERSITY OF HAWAII (US) | 1997-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324620-A1 | CONJUGATES OF THERAPEUTIC OR CYTOTOXIC AGENTS AND BIOLOGICALLY ACTIVE PEPTIDES | MCL1, DNPEP, TP53 | SLC7A5 1208/4885USP2 2524/4885PTGS1 3919/4885 |
| US-20060009622-A1 | Conjugates of therapeutic or cytotoxic agents and biologically active peptides | MCL1, DNPEP, TP53 | SLC7A5 1208/4885USP2 2524/4885PTGS1 3919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.