Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.73 |
| ▸ | USP2 | O75604 | 3/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.73 |
| ▸ | RECQL | P46063 | 2/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | EGFR | P00533 | 1/20 | 0.73 |
| ▸ | LCK | P06239 | 1/20 | 0.73 |
| ▸ | FYN | P06241 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | HTR2A | P28223 | 1/20 | 0.73 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.73 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455225 | 1.00 | SLC7A5 (0.73) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| SCHEMBL2497331 | 1.00 | SLC7A5 (0.73) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| SCHEMBL30552213 | 1.00 | SLC7A5 (0.73) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| SCHEMBL29393527 | 1.00 | SLC7A5 (0.73) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL23574497 | 0.98 | SLC7A5 (0.71) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL23574498 | 0.98 | SLC7A5 (0.71) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| SCHEMBL5297391 | 0.86 | SLC7A5 (0.62) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| Levodopa SCHEMBL116907 | 0.84 | SLC7A5 (1.00) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| Levodopa SCHEMBL20582239 | 0.84 | SLC7A5 (1.00) | SLC7A5USP2PTGS1KDM4EALOX15 | |
| Levodopa SCHEMBL11000382 | 0.84 | SLC7A5 (1.00) | SLC7A5USP2PTGS1KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382646-A1 | ENGINEERED ENZYMES AND METHODS FOR THE SYNTHESIS OF DIVERSE TYROSINE ANALOGS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2025-12-18 | — | — | US | claimed |
| US-12421534-B2 | Engineered enzymes and method for the synthesis of diverse tyrosine analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2025-09-23 | — | — | US | claimed |
| US-12092648-B2 | Detection of glucuronidated and 3-bromotyrosine | THE CLEVELAND CLINIC FOUNDATION (US) | 2024-09-17 | — | — | US | claimed |
| US-20240269228-A1 | SELECTIVE PENICILLAMINE SUBSTITUTION ENABLES DEVELOPMENT OF A POTENT ANALGESIC PEPTIDE THAT ACTS THROUGH A NON-OPIOID BASED MECHANISM | UNIVERSITY OF UTAH RESEARCH FOUNDATION | 2024-08-15 | — | — | US | claimed |
| EP-4346868-A1 | SELECTIVE PENICILLAMINE SUBSTITUTION ENABLES DEVELOPMENT OF A POTENT ANALGESIC PEPTIDE THAT ACTS THROUGH A NON-OPIOID BASED MECHANISM | University of Utah Research Foundation (US) | 2024-04-10 | — | — | EP | claimed |
| US-20230313245-A1 | Engineered Enzymes and Method for the Synthesis of Diverse Tyrosine Analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-10-05 | — | — | US | claimed |
| WO-2023086520-A2 | ENGINEERED ENZYMES AND METHOD FOR THE SYNTHESIS OF DIVERSE TYROSINE ANALOGS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-05-19 | — | — | WO | claimed |
| WO-2022256066-A1 | SELECTIVE PENICILLAMINE SUBSTITUTION ENABLES DEVELOPMENT OF A POTENT ANALGESIC PEPTIDE THAT ACTS THROUGH A NON-OPIOID BASED MECHANISM | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2022-12-08 | — | — | WO | claimed |
| US-20220163540-A1 | DETECTION OF GLUCURONIDATED AND 3-BROMOTYROSINE | THE CLEVELAND CLINIC FOUNDATION | 2022-05-26 | — | — | US | claimed |
| US-11249091-B2 | Detection of glucuronidated and 3-bromotyrosine | THE CLEVELAND CLINIC FOUNDATION (US) | 2022-02-15 | — | — | US | claimed |
| EP-1427845-A2 | METHOD FOR DETECTING SEPSIS | Washington University (US) | 2004-06-16 | — | — | EP | claimed |
| WO-2004021981-A2 | METHODS FOR THE PREPARATION OF β-AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2004-03-18 | — | — | WO | claimed |
| US-20030113882-A1 | Methods for the preparation of beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-06-19 | — | — | US | claimed |
| US-20030100122-A1 | Method for detecting conditions indicative of sepsis | WASHINGTON UNIVERSITY | 2003-05-29 | — | — | US | claimed |
| WO-2003025212-A2 | METHOD FOR DETECTING SEPSIS | WASHINGTON UNIVERSITY (US) | 2003-03-27 | — | — | WO | claimed |
| US-20020048775-A1 | Diagnostic methods for asthma | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2002-04-25 | — | — | US | claimed |
| EP-1159614-A4 | DIAGNOSTIC METHODS FOR ASTHMA | CLEVELAND CLINIC FOUNDATION (US) | 2002-03-27 | — | — | EP | claimed |
| EP-1159614-A1 | DIAGNOSTIC METHODS FOR ASTHMA | THE CLEVELAND CLINIC FOUNDATION (US) | 2001-12-05 | — | — | EP | claimed |
| US-6306576-B1 | ANALYZING SAMPLE FOR 3-BROMOTYROSINE AND/OR 3,5-DIBROMOTYROSINE; ELEVATED LEVELS INDICATE DISEASE ASSOCIATED WITH ACTIVATED EOSINOPHILS | CLEVELAND CLINIC FOUNDATION | 2001-10-23 | — | — | US | claimed |
| WO-2000049411-A1 | DIAGNOSTIC METHODS FOR ASTHMA | THE CLEVELAND CLINIC FOUNDATION (US) | 2000-08-24 | — | — | WO | claimed |