Prenalterol

Prenalterol

SCHEMBL249753

CC(C)NC[C@H](O)COc1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 1.00
SLC6A2 P23975 1/20 1.00
ADRB2 P07550 7/20 0.75
ADRB1 P08588 6/20 0.75
ADRB3 P13945 4/20 0.73
CYP2D6 P10635 4/20 0.73
MAPT P10636 1/20 0.72
OPRK1 P41145 1/20 0.65
MEN1 O00255 1/20 0.65
CYP1A2 P05177 1/20 0.65
ALOX15 P16050 1/20 0.65
TSHR P16473 1/20 0.65
CYP2C19 P33261 1/20 0.65
KMT2A Q03164 1/20 0.65
NR3C1 P04150 1/20 0.65
ADRA1A P35348 1/20 0.65
CYP2J2 P51589 1/20 0.65
PDE4D Q08499 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prenalterol SCHEMBL10788435 1.00 PTGS1 (1.00) PTGS1SLC6A2ADRB2ADRB1ADRB3
Prenalterol SCHEMBL10816429 1.00 PTGS1 (1.00) PTGS1SLC6A2ADRB2ADRB1ADRB3
Prenalterol SCHEMBL11193769 0.98 PTGS1 (0.97) PTGS1SLC6A2ADRB2ADRB1ADRB3
Prenalterol SCHEMBL121857 0.98 PTGS1 (0.97) PTGS1SLC6A2ADRB2ADRB1ADRB3
Prenalterol SCHEMBL1651104 0.97 PTGS1 (0.94) PTGS1SLC6A2ADRB2ADRB1ADRB3
SCHEMBL11284468 0.89 PTGS1 (0.79) PTGS1SLC6A2ADRB2ADRB1ADRB3
SCHEMBL7946116 0.87 PTGS1 (0.77) PTGS1SLC6A2ADRB2ADRB1ADRB3
SCHEMBL22639751 0.87 PTGS1 (0.77) PTGS1SLC6A2ADRB2ADRB1ADRB3
SCHEMBL28403894 0.86 ADRB2 (0.78) PTGS1SLC6A2ADRB2ADRB1ADRB3
SCHEMBL7953135 0.85 PTGS1 (0.74) PTGS1SLC6A2ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2199 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260027139-A1 TREATMENT OF SLEEP APNEA WITH A COMBINATION OF A CARBONIC ANHYDRASE INHIBITOR AND AN ALDOSTERONE ANTAGONIST VIVUS, INC. 2026-01-29 US claimed
US-20250213647-A1 CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE UNIVERSITY OF SOUTH FLORIDA 2025-07-03 US claimed
CN-119233997-A Tetrahedral antibodies 生物分子控股有限责任公司 2024-12-31 CN claimed
US-20240398729-A1 Methods and Compositions for the Treatment of Cytoplasmic Glycogen Storage Disorders DUKE UNIVERSITY (US) 2024-12-05 US claimed
EP-4463485-A2 TETRAHEDRAL ANTIBODIES Biomolecular Holdings LLC (US) 2024-11-20 EP claimed
US-20240366586-A1 METHODS AND AGENTS FOR MODULATING THE IMMUNE RESPONSE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-11-07 US claimed
US-20240139224-A1 TREATMENT OF SLEEP APNEA WITH A COMBINATION OF A CARBONIC ANHYDRASE INHIBITOR AND AN ALDOSTERONE ANTAGONIST AMERICAN ENTERTAINMENT PROPERTIES CORP., AS LENDER 2024-05-02 US claimed
WO-2023192319-A1 CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE UNIVERSITY OF SOUTH FLORIDA (US) 2023-10-05 WO claimed
WO-2023137387-A2 TETRAHEDRAL ANTIBODIES BIOMOLECULAR HOLDINGS LLC (US) 2023-07-20 WO claimed
WO-2023137373-A1 TETRAHEDRAL ANTIBODIES BIOMOLECULAR HOLDINGS LLC (US) 2023-07-20 WO claimed
EP-0954327-A1 USEFUL FORMULATIONS OF ACID ADDITION SALT DRUGS OXIGENE, INC. (US) 1999-11-10 EP claimed
US-5922341-A Local administration of pharmacologically active agents to treat premature ejaculation VIVUS, INCORPORATED (US) 1999-07-13 US claimed
WO-1998000159-A1 USEFUL FORMULATIONS OF ACID ADDITION SALT DRUGS OXIGENE, INC. (US) 1998-01-08 WO claimed
US-5684018-A Acyloxyisopropyl carbamates as prodrugs for amine drugs MERCK & CO., INC. (US) 1997-11-04 US claimed
US-5626854-A XANTHINE OR B-ADRENERGIC STIMULANT KAO CORPORATION (JP) 1997-05-06 US claimed
WO-1996018605-A1 ACYLOXYISOPROPYL CARBAMATES AS PRODRUGS FOR AMINE DRUGS MERCK & CO., INC. (US) 1996-06-20 WO claimed
WO-1995000478-A1 ARYLTRIFLATES AND RELATED COMPOUNDS LUNDBECK & CO AS H (DK) 1995-01-05 WO claimed
WO-1994008579-A1 β-AGONIST, α1-AGONIST, AND/OR α2-ANTAGONIST TREATMENT OF NEURODEGENERATIVE DISEASES AND CENTRAL NERVOUS SYSTEM TRAUMA NEW YORK UNIVERSITY (US) 1994-04-28 WO claimed
US-4980159-A EFFECTING RETRACTION OF HAIR; AFTERSHAVING LIQUIDS; DEPILATORIES BRISTOL-MYERS SQUIBB COMPANY (US) 1990-12-25 US claimed
EP-0152379-A2 Process for preparing pharmaceutical compositions containing unilamellar liposomes CIBA-GEIGY AG (CH) 1985-08-21 EP claimed