Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22851668 | 0.83 | MRGPRX4 (0.43) | HTR2CSLC6A4HTR2BMAPTL3MBTL1 | |
| SCHEMBL26618377 | 0.83 | SYK (0.42) | HTR2CSLC6A4HTR2BMAPTL3MBTL1 | |
| SCHEMBL31339028 | 0.83 | SYK (0.42) | HTR2CSLC6A4HTR2BMAPTL3MBTL1 | |
| SCHEMBL24975462 | 0.83 | SMN1; SMN2 (0.52) | HTR2CSLC6A4HTR2BMAPTL3MBTL1 | |
| SCHEMBL31304967 | 0.80 | TRPV1 (0.43) | L3MBTL1MAPK1SYKLTA4HHTT | |
| SCHEMBL31339058 | 0.80 | NPC1 (0.39) | HTR2CSLC6A4HTR2BMAPTL3MBTL1 | |
| SCHEMBL31339021 | 0.80 | NPC1 (0.48) | HTR2CSLC6A4HTR2BMAPTL3MBTL1 | |
| SCHEMBL26618448 | 0.80 | NPC1 (0.48) | HTR2CSLC6A4HTR2BMAPTL3MBTL1 | |
| SCHEMBL26618637 | 0.80 | NPC1 (0.39) | HTR2CSLC6A4HTR2BMAPTL3MBTL1 | |
| SCHEMBL24976600 | 0.79 | SLC6A4 (0.43) | HTR2CSLC6A4HTR2BMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023005894-A1 | INHIBITOR COMPOUND FOR WNT PATHWAY | 杭州阿诺生物医药科技有限公司 | 2023-02-02 | — | — | WO | disclosed |