Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26618377 | 1.00 | SYK (0.42) | SYKHTR2CSLC6A4HTR2BMAPT | |
| SCHEMBL24975372 | 0.83 | HTR2C (0.41) | SYKHTR2CSLC6A4HTR2BMAPT | |
| SCHEMBL22851668 | 0.82 | MRGPRX4 (0.43) | SYKHTR2CSLC6A4HTR2BMAPT | |
| SCHEMBL24975462 | 0.82 | SMN1; SMN2 (0.52) | SYKHTR2CSLC6A4HTR2BMAPT | |
| SCHEMBL26618637 | 0.78 | NPC1 (0.39) | SYKHTR2CSLC6A4HTR2BMAPT | |
| SCHEMBL31339058 | 0.78 | NPC1 (0.39) | SYKHTR2CSLC6A4HTR2BMAPT | |
| SCHEMBL26618448 | 0.78 | NPC1 (0.48) | SYKHTR2CSLC6A4HTR2BMAPT | |
| SCHEMBL31339021 | 0.78 | NPC1 (0.48) | SYKHTR2CSLC6A4HTR2BMAPT | |
| SCHEMBL2435879 | 0.78 | L3MBTL1 (0.44) | SLC6A4MAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL24976600 | 0.77 | SLC6A4 (0.43) | SYKHTR2CSLC6A4HTR2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250296939-A1 | BENZOTHIOPHENE COMPOUND | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2025-09-25 | — | — | US | disclosed |
| EP-4516792-A1 | BENZOTHIOPHENE COMPOUND | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2025-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250296939-A1 | BENZOTHIOPHENE COMPOUND | NFE2L2, KEAP1, BPTF | SYK 3053/4885HTR2C 2885/4885SLC6A4 2843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.