Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 6/20 | 0.36 |
| ▸ | EGFR | P00533 | 5/20 | 0.36 |
| ▸ | CFTR | P13569 | 4/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24542476 | 0.91 | FLT3 (0.41) | EHMT2HDAC4HDAC6USP30FGFR3 | |
| SCHEMBL24542471 | 0.91 | FLT3 (0.41) | EHMT2HDAC4HDAC6USP30FGFR3 | |
| SCHEMBL24975704 | 0.88 | CFTR (0.35) | EHMT2CFTRSYKPIK3CDRIPK1 | |
| SCHEMBL26661906 | 0.88 | CFTR (0.35) | EHMT2CFTRSYKPIK3CDRIPK1 | |
| SCHEMBL24542627 | 0.83 | FLT3 (0.43) | CFTRUSP30KDRPIM1PIM2 | |
| SCHEMBL24542628 | 0.83 | FLT3 (0.43) | CFTRUSP30KDRPIM1PIM2 | |
| SCHEMBL24975906 | 0.83 | SYK (0.39) | EHMT2BTKEGFRSYKPIK3CD | |
| SCHEMBL24976599 | 0.83 | SYK (0.39) | EHMT2BTKEGFRSYKPIK3CD | |
| SCHEMBL24977595 | 0.82 | HDAC4 (0.38) | HDAC4HDAC6BTKEGFRSYK | |
| SCHEMBL24977598 | 0.82 | HDAC4 (0.38) | HDAC4HDAC6BTKEGFRSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009833-A9 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023009833-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2023-02-02 | — | — | WO | disclosed |