Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 15/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | FES | P07332 | 1/20 | 0.36 |
| ▸ | ROS1 | P08922 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428800 | 1.00 | SLC6A2 (0.48) | SLC6A2SLC6A4KCNH2SLC6A3F10 | |
| SCHEMBL31428916 | 0.86 | KCNH2 (0.51) | SLC6A2SLC6A4KCNH2SLC6A3F10 | |
| SCHEMBL31428702 | 0.84 | NPC1 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31428457 | 0.81 | SLC6A2 (0.48) | SLC6A2SLC6A4KCNH2SLC6A3F10 | |
| SCHEMBL24975787 | 0.81 | SLC6A2 (0.39) | SLC6A2SLC6A4KCNH2SLC6A3F10 | |
| SCHEMBL31428905 | 0.70 | KMT2A (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31428722 | 0.69 | HRH3 (0.45) | — | |
| SCHEMBL24977045 | 0.69 | HRH3 (0.45) | — | |
| SCHEMBL31429036 | 0.68 | HRH3 (0.44) | SLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL24975620 | 0.66 | SLC6A2 (0.51) | SLC6A2SLC6A4KCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |