Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428457 | 0.92 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3KCNH2SCN9A | |
| SCHEMBL31428702 | 0.84 | NPC1 (0.39) | SLC6A2SLC6A4SLC6A3SCN9AALDH1A1 | |
| SCHEMBL31428800 | 0.81 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3KCNH2F10 | |
| SCHEMBL24975790 | 0.81 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3KCNH2F10 | |
| SCHEMBL31428673 | 0.77 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3KCNH2PIK3CD | |
| SCHEMBL24975620 | 0.77 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3KCNH2PIK3CD | |
| SCHEMBL31428473 | 0.71 | MAPT (0.37) | SLC6A2SLC6A4SLC6A3KCNH2MEN1 | |
| SCHEMBL30163473 | 0.70 | NR1H4 (0.38) | SLC6A2SLC6A4SLC6A3KCNH2SCN9A | |
| SCHEMBL24975808 | 0.69 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3KCNH2KMT2A | |
| SCHEMBL24977045 | 0.69 | HRH3 (0.45) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |