Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | ROS1 | P08922 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | MARK3 | P27448 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.41 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428549 | 1.00 | ERN1 (0.47) | ERN1MEN1RAB9AKMT2AHPGD | |
| SCHEMBL31428507 | 0.91 | GRM2 (0.47) | ERN1MEN1RAB9AKMT2AHPGD | |
| SCHEMBL24975793 | 0.91 | GRM2 (0.47) | ERN1MEN1RAB9AKMT2AHPGD | |
| SCHEMBL31428552 | 0.89 | MEN1 (0.46) | ERN1MEN1RAB9AKMT2AHPGD | |
| SCHEMBL31428482 | 0.85 | HPGD (0.41) | RAB9AKMT2AHPGDTSHR | |
| SCHEMBL24975789 | 0.85 | HPGD (0.41) | RAB9AKMT2AHPGDTSHR | |
| SCHEMBL31428481 | 0.85 | ERN1 (0.52) | ERN1MEN1RAB9AKMT2AHPGD | |
| SCHEMBL31428711 | 0.84 | GRM2 (0.51) | ERN1HPGDJAK2GRM2TSHR | |
| SCHEMBL24976130 | 0.84 | PDCD1 (0.42) | ERN1MEN1RAB9AKMT2AHPGD | |
| SCHEMBL31428977 | 0.84 | PDCD1 (0.42) | ERN1MEN1RAB9AKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |