Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24975643 | 0.88 | HSP90AA1 (0.48) | HPGDALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL31428660 | 0.88 | HSP90AA1 (0.48) | HPGDALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL31428645 | 0.80 | HPGD (0.57) | HPGDALDH1A1KDM4ETSHRGAA | |
| SCHEMBL31428677 | 0.80 | HTR2C (0.53) | HPGDALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL31428895 | 0.79 | KMT2A (0.42) | HPGDALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL22353354 | 0.78 | HPGD (0.56) | HPGDALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL12311738 | 0.74 | HPGD (0.77) | HPGDALDH1A1KDM4ETSHRGAA | |
| SCHEMBL15262556 | 0.74 | HPGD (0.59) | HPGDALDH1A1KDM4ETSHRGAA | |
| SCHEMBL15263012 | 0.74 | HPGD (0.59) | HPGDALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL8050723 | 0.74 | HPGD (0.59) | HPGDALDH1A1KDM4ETSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |