Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24975643 | 1.00 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1HPGDKDM4EALDH1A1 | |
| SCHEMBL24975811 | 0.88 | HPGD (0.52) | HSP90AA1HSP90AB1HPGDKDM4EALDH1A1 | |
| SCHEMBL31428645 | 0.79 | HPGD (0.57) | HSP90AA1HSP90AB1HPGDKDM4EALDH1A1 | |
| SCHEMBL31428677 | 0.79 | HTR2C (0.53) | HPGDKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL31428895 | 0.78 | KMT2A (0.42) | HPGDKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL22353354 | 0.77 | HPGD (0.56) | HSP90AA1HSP90AB1HPGDKDM4EALDH1A1 | |
| SCHEMBL16533303 | 0.74 | METAP2 (0.49) | HPGDKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL31471661 | 0.74 | SERPINE1 (0.75) | HSP90AA1HSP90AB1HPGDKDM4ETSHR | |
| SCHEMBL16302094 | 0.72 | HPGD (0.62) | HSP90AA1HSP90AB1HPGDKDM4EALDH1A1 | |
| SCHEMBL20260141 | 0.72 | HPGD (0.58) | HSP90AA1HPGDKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | HSP90AA1 1521/4885HSP90AB1 845/4885HPGD 4233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.