Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | AXL | P30530 | 4/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428805 | 1.00 | GRM2 (0.49) | GRM2EPHX2AXLBRD4KDM4E | |
| SCHEMBL31428997 | 0.80 | GRM2 (0.51) | GRM2EPHX2AXLBRD4KDM4E | |
| SCHEMBL1773091 | 0.78 | NUDT1 (0.60) | KDM4EALDH1A1HTTMAPTHPGD | |
| SCHEMBL31428664 | 0.77 | GRM4 (0.65) | GRM2EPHX2AXLBRD4GRM4 | |
| SCHEMBL17942808 | 0.76 | AXL (0.49) | GRM2EPHX2AXLBRD4KDM1A | |
| SCHEMBL29986553 | 0.75 | ADORA2A (0.57) | KDM4EALDH1A1HTTMAPTHPGD | |
| SCHEMBL16542819 | 0.75 | ADORA2A (0.57) | KDM4EALDH1A1HTTMAPTHPGD | |
| SCHEMBL17942680 | 0.75 | BRD4 (0.44) | GRM2EPHX2AXLBRD4MAPT | |
| SCHEMBL31429051 | 0.75 | GRM2 (0.64) | GRM2EPHX2BRD4KDM4EALDH1A1 | |
| SCHEMBL24977215 | 0.75 | GRM2 (0.64) | GRM2EPHX2BRD4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |