Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 9/20 | 0.33 |
| ▸ | MET | P08581 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 7/20 | 0.32 |
| ▸ | IRAK1 | P51617 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
| ▸ | MST1R | Q04912 | 1/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428533 | 1.00 | CREBBP (0.33) | CREBBPMETBRD4IRAK1MAPK1 | |
| SCHEMBL31428785 | 0.96 | PDE9A (0.34) | CREBBPMETBRD4MAPK1MST1R | |
| SCHEMBL31428693 | 0.94 | ALDH1A1 (0.33) | MAPK1 | |
| SCHEMBL24976132 | 0.89 | ALDH1A1 (0.34) | MAPK1 | |
| SCHEMBL31428821 | 0.86 | IRAK1 (0.36) | CREBBPMETBRD4IRAK1MAPK1 | |
| SCHEMBL24975439 | 0.86 | IRAK1 (0.36) | CREBBPMETBRD4IRAK1MAPK1 | |
| SCHEMBL31428765 | 0.84 | ALDH1A1 (0.32) | MAPK1 | |
| SCHEMBL31428763 | 0.84 | PDCD1 (0.44) | CREBBPMETIRAK1MAPK1IRAK4 | |
| SCHEMBL24975829 | 0.84 | MAPK1 (0.32) | CREBBPMAPK1 | |
| SCHEMBL31428620 | 0.84 | MAPK1 (0.32) | CREBBPMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |