Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20449044 | 0.88 | HPGD (0.87) | HPGDTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL4548025 | 0.85 | TSHR (1.00) | HPGDTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL104400 | 0.85 | KMT2A (0.78) | HPGDTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL104359 | 0.82 | HPGD (0.60) | HPGDTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL6345968 | 0.81 | HPGD (0.75) | HPGDTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL12591836 | 0.81 | KMT2A (0.71) | HPGDTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL17465250 | 0.79 | KMT2A (0.85) | HPGDTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL2378399 | 0.79 | HPGD (0.73) | HPGDTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL14200320 | 0.79 | KMT2A (0.54) | HPGDTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL10495198 | 0.78 | ALDH1A1 (0.89) | HPGDMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009833-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2023-02-02 | — | — | WO | disclosed |