Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.43 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2495902 | 0.89 | POLB (0.47) | LMNAMEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL2495414 | 0.89 | MLLT3 (0.46) | LMNAMEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL2497680 | 0.87 | CYP2D6 (0.48) | HPGDPOLBUSP30ALDH1A1HTT | |
| SCHEMBL1879440 | 0.83 | MEN1 (0.51) | MEN1KMT2AALDH1A1TUBB4ATUBB | |
| SCHEMBL2498081 | 0.83 | MLLT3 (0.46) | LMNAMEN1KMT2AHPGDPOLB | |
| SCHEMBL2497173 | 0.83 | MLLT3 (0.46) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL2496574 | 0.82 | MAPT (0.49) | LMNAMEN1KMT2AUSP30ALDH1A1 | |
| SCHEMBL2498711 | 0.81 | MLLT3 (0.41) | LMNAMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL12191226 | 0.80 | SMN1; SMN2 (0.51) | MEN1KMT2AHPGDALDH1A1TUBB4A | |
| SCHEMBL1880372 | 0.78 | TP53 (0.48) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030339-B2 | Imidazole derivatives for the treatment of anxiety and related diseases | NEUROSEARCH A/S (DK) | 2011-10-04 | — | — | US | disclosed |