Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2498711 | 0.89 | MLLT3 (0.41) | SMN1; SMN2NPC1TP53RAB9ATUBB4A | |
| SCHEMBL2497173 | 0.89 | MLLT3 (0.46) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2497658 | 0.87 | LMNA (0.45) | NPC1HPGDTUBB4ATUBBTUBA3C | |
| SCHEMBL2498081 | 0.81 | MLLT3 (0.46) | SMN1; SMN2NPC1RAB9AHPGDTUBB4A | |
| SCHEMBL1879440 | 0.81 | MEN1 (0.51) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2495902 | 0.79 | POLB (0.47) | SMN1; SMN2HPGDTUBB4ATUBBTUBA3C | |
| SCHEMBL2495414 | 0.78 | MLLT3 (0.46) | SMN1; SMN2HPGDKDM4EPOLBALDH1A1 | |
| SCHEMBL12191226 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDTUBB4ATUBBTUBA3C | |
| SCHEMBL13753671 | 0.76 | HPGD (0.64) | CYP2D6CYP2C9CYP2C19RECQLSMN1; SMN2 | |
| SCHEMBL1880372 | 0.76 | TP53 (0.48) | SMN1; SMN2TP53TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030339-B2 | Imidazole derivatives for the treatment of anxiety and related diseases | NEUROSEARCH A/S (DK) | 2011-10-04 | — | — | US | disclosed |