Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428501 | 1.00 | CCNC (0.49) | CCNCCDK8HPGDGRM2AR | |
| SCHEMBL31428866 | 0.88 | CCNC (0.58) | CCNCCDK8HPGDGRM2AR | |
| SCHEMBL31428969 | 0.88 | CCNC (0.49) | CCNCCDK8HPGDGRM2AR | |
| SCHEMBL31428513 | 0.83 | PDCD1 (0.53) | HPGDGRM2KDM4EALDH1A1PKM | |
| SCHEMBL30163641 | 0.82 | CCNC (0.54) | CCNCCDK8HPGDGRM2KDM4E | |
| SCHEMBL31429010 | 0.82 | AR (0.61) | CCNCCDK8HPGDGRM2AR | |
| SCHEMBL31428786 | 0.82 | CCNC (0.44) | CCNCCDK8HPGDGRM2AR | |
| SCHEMBL31429061 | 0.81 | CCNC (0.56) | CCNCCDK8HPGDPIK3CDMEN1 | |
| SCHEMBL31428834 | 0.81 | GRM2 (0.48) | HPGDGRM2ARKDM4EALDH1A1 | |
| SCHEMBL31429056 | 0.81 | MAPT (0.54) | HPGDARALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |