Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 7/20 | 0.54 |
| ▸ | CDK8 | P49336 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428866 | 0.93 | CCNC (0.58) | CCNCCDK8HPGDGRM2KDM4E | |
| SCHEMBL31428537 | 0.89 | PDCD1 (0.52) | HPGDPDCD1CD274KDM4EUSP2 | |
| SCHEMBL31428426 | 0.88 | CCNC (0.54) | CCNCCDK8HPGDGRM2PDK2 | |
| SCHEMBL24977242 | 0.88 | CCNC (0.54) | CCNCCDK8HPGDGRM2PDK2 | |
| SCHEMBL31429061 | 0.88 | CCNC (0.56) | CCNCCDK8HPGDPDCD1CD274 | |
| SCHEMBL31428513 | 0.84 | PDCD1 (0.53) | HPGDPDCD1CD274GRM2KDM4E | |
| SCHEMBL31428786 | 0.83 | CCNC (0.44) | CCNCCDK8HPGDPDCD1CD274 | |
| SCHEMBL31428699 | 0.82 | HTR2C (0.53) | HPGDPDCD1CD274KDM4EUSP2 | |
| SCHEMBL31428501 | 0.82 | CCNC (0.49) | CCNCCDK8HPGDGRM2KDM4E | |
| SCHEMBL24977216 | 0.82 | CCNC (0.49) | CCNCCDK8HPGDGRM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | CCNC 1310/4885CDK8 1499/4885HPGD 4233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.