SCHEMBL24977285

SCHEMBL24977285

CC(C)C(=O)COCCOCCNC(=O)NCCCCNC(=O)CCCNC(=O)CCCCCCCCCCCCCCCCC=O

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.41
EPHX2 P34913 7/20 0.40
SLC6A5 Q9Y345 2/20 0.37
LPAR1 Q92633 2/20 0.37
LPAR2 Q9HBW0 2/20 0.37
ENPP2 Q13822 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24977644 0.87 GLP1R (0.52) GLP1REPHX2
SCHEMBL24977282 0.87 PRMT1 (0.48) GLP1REPHX2
SCHEMBL24977309 0.86 GLP1R (0.36) GLP1REPHX2SLC6A5LPAR1LPAR2
SCHEMBL19092129 0.80 GLP1R (0.45) GLP1REPHX2SLC6A5LPAR1LPAR2
SCHEMBL24489570 0.80 GLP1R (0.49) GLP1REPHX2SLC6A5
SCHEMBL18560499 0.80 LPAR1 (0.46) EPHX2SLC6A5LPAR1LPAR2ENPP2
SCHEMBL25110213 0.78 TSHR (0.50) GLP1RLPAR1LPAR2ENPP2
SCHEMBL25108983 0.78 TSHR (0.50) GLP1RLPAR1LPAR2ENPP2
SCHEMBL25110239 0.78 TSHR (0.50) GLP1RLPAR1LPAR2ENPP2
SCHEMBL18560570 0.78 LPAR1 (0.41) EPHX2SLC6A5LPAR1LPAR2ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122954-A1 NOVEL GLP-1 ANALOGUES Sun Pharmaceutical Industries Limited (IN) 2023-01-25 EP disclosed