SCHEMBL24977309

SCHEMBL24977309

CC(C)C(=O)COCCOCCNC(=O)C(C)(C)NC(=O)CCCNC(=O)CCCCCCCCCCCCCCCCC=O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.36
LPAR1 Q92633 3/20 0.34
LPAR2 Q9HBW0 2/20 0.34
ENPP2 Q13822 1/20 0.34
KDM4E B2RXH2 1/20 0.33
EPHX2 P34913 2/20 0.32
SLC6A5 Q9Y345 2/20 0.32
CNR1 P21554 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24489740 0.89 GLP1R (0.41) GLP1RKDM4EEPHX2SLC6A5
SCHEMBL24977285 0.86 GLP1R (0.41) GLP1RLPAR1LPAR2ENPP2EPHX2
SCHEMBL23583069 0.77 GLP1R (0.41) GLP1RKDM4EEPHX2SLC6A5
SCHEMBL24977646 0.77 GLP1R (0.46) GLP1RLPAR1LPAR2ENPP2
SCHEMBL19092129 0.76 GLP1R (0.45) GLP1RLPAR1LPAR2ENPP2KDM4E
SCHEMBL24489570 0.76 GLP1R (0.49) GLP1RKDM4EEPHX2SLC6A5
SCHEMBL22675549 0.76 GLP1R (0.41) GLP1RKDM4EEPHX2SLC6A5
SCHEMBL22675659 0.76 GLP1R (0.52) GLP1R
SCHEMBL18560499 0.75 LPAR1 (0.46) LPAR1LPAR2ENPP2KDM4EEPHX2
SCHEMBL25110213 0.74 TSHR (0.50) GLP1RLPAR1LPAR2ENPP2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122954-A1 NOVEL GLP-1 ANALOGUES Sun Pharmaceutical Industries Limited (IN) 2023-01-25 EP disclosed