Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.36 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.36 |
| ▸ | CACNA2D4 | Q7Z3S7 | 1/20 | 0.36 |
| ▸ | CACNA2D3 | Q8IZS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30101584 | 1.00 | PIK3CD (0.37) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL30634789 | 0.85 | PIK3CD (0.39) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL30101547 | 0.84 | BTK (0.36) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL24977610 | 0.84 | BTK (0.36) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL30634772 | 0.84 | PIK3CD (0.39) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL30634781 | 0.83 | JAK1 (0.38) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL30634799 | 0.82 | PIK3CD (0.36) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL24978460 | 0.79 | PIK3CD (0.36) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL30101588 | 0.79 | PIK3CD (0.36) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL25937394 | 0.78 | MCHR1 (0.36) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230310423-A1 | CHECKPOINT KINASE 1 (CHK1) INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. | 2023-10-05 | — | — | US | disclosed |
| US-11707462-B2 | Checkpoint kinase 1 (CHK1) inhibitors and uses thereof | BOUNDLESS BIO, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-20230026313-A1 | CHECKPOINT KINASE 1 (CHK1) INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230310423-A1 | CHECKPOINT KINASE 1 (CHK1) INHIBITORS AND USES THEREOF | CHEK1, CHEK2, RAD1 | PIK3CD 836/4885CACNB4 4539/4885CACNA1A 4875/4885 |
| US-11707462-B2 | Checkpoint kinase 1 (CHK1) inhibitors and uses thereof | CHEK1, CHEK2, RAD1 | PIK3CD 836/4885CACNB4 4539/4885CACNA1A 4875/4885 |
| US-20230026313-A1 | CHECKPOINT KINASE 1 (CHK1) INHIBITORS AND USES THEREOF | CHEK1, CHEK2, RAD1 | PIK3CD 836/4885CACNB4 4539/4885CACNA1A 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.