Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.36 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.36 |
| ▸ | CACNA2D4 | Q7Z3S7 | 1/20 | 0.36 |
| ▸ | CACNA2D3 | Q8IZS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30634789 | 0.90 | PIK3CD (0.39) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL26670605 | 0.90 | LDHA (0.32) | CCNE1CDK2 | |
| SCHEMBL30634781 | 0.86 | JAK1 (0.38) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL24977758 | 0.82 | PIK3CD (0.37) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL30101584 | 0.82 | PIK3CD (0.37) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL30101547 | 0.80 | BTK (0.36) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL24977610 | 0.80 | BTK (0.36) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL26670746 | 0.80 | LDHA (0.36) | PIK3CDPDE4BCCNE1CDK2 | |
| SCHEMBL30634783 | 0.79 | AURKA (0.36) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL30634772 | 0.77 | PIK3CD (0.39) | PIK3CDCACNB4CACNA1ACACNA1GCACNG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532486-A1 | PYRIDINE CHECKPOINT KINASE 1 (CHK1) INHIBITORS AND USES THEREOF | Boundless Bio, Inc. (US) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023230477-A1 | PYRIDINE CHECKPOINT KINASE 1 (CHK1) INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. (US) | 2023-11-30 | — | — | WO | disclosed |