Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.52 |
| ▸ | PIK3C3 | Q8NEB9 | 11/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251481 | 1.00 | MTOR (0.52) | MTORPIK3C3LRRK2HRH3KCNH2 | |
| SCHEMBL249781 | 1.00 | MTOR (0.52) | MTORPIK3C3LRRK2HRH3KCNH2 | |
| SCHEMBL2599489 | 0.82 | MTOR (0.53) | MTORPIK3C3LRRK2 | |
| SCHEMBL21256945 | 0.81 | PIK3C3 (0.50) | MTORPIK3C3 | |
| SCHEMBL26515061 | 0.81 | PIK3C3 (0.50) | MTORPIK3C3 | |
| SCHEMBL27962179 | 0.81 | KDM4E (0.44) | MTORHRH3KCNH2 | |
| SCHEMBL25018626 | 0.80 | MTOR (0.50) | MTORPIK3C3 | |
| SCHEMBL24681530 | 0.80 | MTOR (0.50) | MTORPIK3C3 | |
| SCHEMBL22296389 | 0.80 | PIK3C3 (0.49) | PIK3C3 | |
| SCHEMBL24681517 | 0.80 | MTOR (0.50) | MTORPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-B1 | NAPHTHYRIDINE DERIVATIVES HAVING BRONCHODILATING ACTIVITY | RESPIRATORIUS AB (SE) | 2013-07-24 | — | — | EP | disclosed |
| US-8415333-B2 | Bronchodilating diazaheteroaryls | RESPIRATORIOUS AB (SE) | 2013-04-09 | — | — | US | disclosed |
| US-20120040942-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | RESPIRATORIUS AB (SE) | 2012-02-16 | — | — | US | disclosed |
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097410-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | RESPIRATORIUS AB (SE) | 2010-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040942-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | CHRM3, ADRB1, ADRB3 | MTOR 4059/4885PIK3C3 4884/4885LRRK2 4682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.