Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24978425 | 0.96 | HSD17B10 (0.47) | HSD17B10KDM4EKMT2ATSHRALDH1A1 | |
| SCHEMBL24978420 | 0.85 | HSD17B10 (0.47) | HDAC3HDAC1HDAC2HSD17B10KDM4E | |
| SCHEMBL24978407 | 0.83 | HDAC3 (0.43) | HDAC3HDAC1HDAC2KMT2ATSHR | |
| SCHEMBL24978426 | 0.82 | HSD17B10 (0.51) | HSD17B10KDM4EKMT2ATSHRALDH1A1 | |
| SCHEMBL23330999 | 0.80 | HDAC3 (0.40) | HDAC3HDAC1HDAC2KMT2ATSHR | |
| SCHEMBL23300902 | 0.80 | MAP4K1 (0.42) | KMT2AHPGDSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL23331078 | 0.80 | HDAC1 (0.49) | HDAC3HDAC1HDAC2KMT2A | |
| SCHEMBL23330650 | 0.78 | HDAC1 (0.47) | HDAC3HDAC1HDAC2KMT2A | |
| SCHEMBL24978674 | 0.78 | HDAC1 (0.42) | HDAC3HDAC1HDAC2 | |
| SCHEMBL23331082 | 0.74 | HTT (0.39) | KDM4EKMT2AALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230028221-A1 | EED INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | JING MEDICINE TECHNOLOGY (SHANGHAI) LTD. (CN) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230028221-A1 | EED INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP4F11, CYP4A11, HSD11B1 | HDAC3 3383/4885HDAC1 1446/4885HDAC2 2456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.