Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP5K1C | O60331 | 5/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | PIP5K1B | O14986 | 1/20 | 0.41 |
| ▸ | PIP5K1A | Q99755 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | WNT1 | P04628 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23330648 | 0.92 | HDAC3 (0.46) | PIP5K1CPIK3CAMAPK10MAPK8MAPK14 | |
| SCHEMBL23331087 | 0.92 | HDAC1 (0.47) | MAPK10MAPK8MAPK14HDAC1HDAC2 | |
| SCHEMBL24978674 | 0.85 | HDAC1 (0.42) | PIP5K1CPIK3CAMAPK10MAPK8MAPK14 | |
| SCHEMBL23301458 | 0.84 | ABL1 (0.45) | ABL1 | |
| SCHEMBL24978408 | 0.82 | KMT2A (0.46) | HDAC1HDAC2HDAC3ABL1 | |
| SCHEMBL23331000 | 0.82 | MEN1 (0.43) | HDAC1HDAC2HDAC3ABL1POLB | |
| SCHEMBL23330650 | 0.78 | HDAC1 (0.47) | PIP5K1CPIK3CAMAPK10MAPK8MAPK14 | |
| SCHEMBL23331078 | 0.77 | HDAC1 (0.49) | HDAC1HDAC2HDAC3ABL1P2RX3 | |
| SCHEMBL24978426 | 0.76 | HSD17B10 (0.51) | — | |
| SCHEMBL24978420 | 0.75 | HSD17B10 (0.47) | HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230028221-A1 | EED INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | JING MEDICINE TECHNOLOGY (SHANGHAI) LTD. (CN) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230028221-A1 | EED INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP4F11, CYP4A11, HSD11B1 | PIP5K1C 4534/4885PIK3CA 2963/4885MAPK10 3264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.