SCHEMBL2498083

SCHEMBL2498083

[O]CC=CC(Cl)(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2498080 1.00
SCHEMBL10679983 0.69
SCHEMBL18853753 0.69
SCHEMBL28859286 0.67 ALDH1A1 (0.30)
SCHEMBL6671881 0.67
SCHEMBL2494482 0.67
SCHEMBL6671883 0.67
SCHEMBL10400172 0.67
SCHEMBL2494480 0.67
SCHEMBL6671879 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8030529-B2 Process for the preparation of intermediates SYNGENTA CROP PROTECTION, INC. (US) 2011-10-04 US disclosed
EP-1567482-B1 PROCESS FOR THE PREPARATION OF PHENYLMALONIC ACID DINITRILES SYNGENTA PARTICIPATIONS AG (CH) 2010-02-17 EP disclosed
US-20090023964-A1 PROCESS FOR THE PREPARATION OF INTERMEDIATES SYNGENTA CROP PROTECTION, INC. (US) 2009-01-22 US disclosed
EP-1848678-A1 PROCESS FOR THE PREPARATION OF INTERMEDIATES Syngeta Participations AG (CH) 2007-10-31 EP disclosed
US-7268247-B2 Process for the preparation of phenylmalonic acid dinitriles SYNGENTA CROP PROTECTION, INC. (US) 2007-09-11 US disclosed
WO-2006084663-A1 PROCESS FOR THE PREPARATION OF INTERMEDIATES SYNGENTA PARTICIPATIONS AG (CH) 2006-08-17 WO disclosed
US-20060135805-A1 Process for the preparation of phenylmalonic acid dinitriles SYNGENTA CROP PROTECTION, INC. 2006-06-22 US disclosed
EP-1567482-A1 PROCESS FOR THE PREPARATION OF PHENYLMALONIC ACID DINITRILES Syngenta Participations AG (CH) 2005-08-31 EP disclosed
US-20040198797-A1 Process for the preparation of herbicidal derivatives MAETZKE THOMAS (CH) 2004-10-07 US disclosed
WO-2004050607-A1 PROCESS FOR THE PREPARATION OF PHENYLMALONIC ACID DINITRILES SYNGENTA PARTICIPATIONS AG (CH) 2004-06-17 WO disclosed
EP-1183317-A2 PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES Syngenta Participations AG (CH) 2002-03-06 EP disclosed
EP-0929543-B1 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2001-10-31 EP disclosed
US-6294504-B1 ANTIDOTES FOR HERBICIDES SYNGENTA CROP PROTECTION, INC. 2001-09-25 US disclosed
US-6274536-B1 CROPS, AGRICULTURE; PRE- AND POSTEMERGENCE SYNGENTA CROP PROTECTION, INC. 2001-08-14 US disclosed
EP-1076655-A1 N-PYRIDONYL HERBICIDES Novartis AG (CH) 2001-02-21 EP disclosed
WO-2000078712-A1 SUBSTITUTED ARYLMALONIC ACID DINITRILES AS INTERMEDIATES FOR THE PREPARTION OF HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2000-12-28 WO disclosed
WO-2000078881-A2 PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES SYGENTA PARTICIPATIONS AG (CH) 2000-12-28 WO disclosed
EP-0966461-A1 PYRAZOLE DERIVATIVES AS HERBICIDES Novartis AG (CH) 1999-12-29 EP disclosed
WO-1999052893-A1 N-PYRIDONYL HERBICIDES NOVARTIS AG (CH) 1999-10-21 WO disclosed
WO-1998042698-A1 PYRAZOLE DERIVATIVES AS HERBICIDES NOVARTIS AG (CH) 1998-10-01 WO disclosed