Alfadex

Alfadex

SCHEMBL24981

OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@@H](O[C@H]5[C@H](O)[C@@H](O)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@@H](O[C@H]7[C@H](O)[C@@H](O)[C@@H](O[C@H]1[C@H](O)[C@H]2O)O[C@@H]7CO)O[C@@H]6CO)O[C@@H]5CO)O[C@@H]4CO)O[C@@H]3CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 1.00
TSHR P16473 2/20 1.00
LMNA P02545 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
TXNRD1 Q16881 6/20 0.77
TXNRD3 Q86VQ6 6/20 0.77
TXNRD2 Q9NNW7 6/20 0.77
HDAC3 O15379 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC2 Q92769 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
FYN P06241 1/20 0.47
MAOA P21397 1/20 0.47
SLC6A2 P23975 1/20 0.47
HTR2C P28335 1/20 0.47
HTR2B P41595 1/20 0.47
SLC6A3 Q01959 1/20 0.47
LGALS1 P09382 2/20 0.37
LGALS3 P17931 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alfadex SCHEMBL21134960 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNATDP1TXNRD1
Gamma-Cyclodextrin SCHEMBL25455463 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNATDP1TXNRD1
Betadex SCHEMBL24109285 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNATDP1TXNRD1
Gamma-Cyclodextrin SCHEMBL20533920 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNATDP1TXNRD1
Gamma-Cyclodextrin SCHEMBL25455531 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNATDP1TXNRD1
Alfadex SCHEMBL23188277 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNATDP1TXNRD1
Alfadex SCHEMBL24109286 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNATDP1TXNRD1
Alfadex SCHEMBL25455476 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNATDP1TXNRD1
Betadex SCHEMBL23188251 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNATDP1TXNRD1
Gamma-Cyclodextrin SCHEMBL20998969 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNATDP1TXNRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 38632 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122081031-A Method for improving stability of flavone in tartary buckwheat wine 2026-05-26 CN claimed
CN-122075340-A Oil-control acne-removing antibacterial peptide co-amorphous assembly, and preparation method and application thereof 2026-05-26 CN claimed
CN-116515147-B Topological cyclodextrin/chitosan composite membrane and preparation method and application thereof Jiangsu Jicui Special Medical Food Technology Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122084727-A Method for detecting and separating eight flavonoid glycoside compounds with similar structures by utilizing capillary zone electrophoresis 2026-05-26 CN claimed
CN-122091800-A High-adhesiveness wide-temperature-range aqueous zinc ion battery hydrogel electrolyte and preparation method and application thereof 2026-05-26 CN claimed
CN-122038529-A Sugar molecule sequencing method based on glycosidase and nano-pore, system and application thereof 中国科学院上海药物研究所 2026-05-15 CN claimed
CN-122037314-A Preparation method and application of mesoporous silica/ammonium polyphosphate flame-retardant particles with core-shell structure 北京理工大学 2026-05-15 CN claimed
CN-122037849-A Epoxy resin adhesive and preparation method and application thereof 广东德泽新材料科技有限公司 2026-05-15 CN claimed
CN-122030429-A Compound disinfectant based on single-chain and double-chain quaternary ammonium salt and plant essential oil and preparation method thereof 苏州拜革环能科技有限公司 2026-05-15 CN claimed
CN-122034460-A Anti-puncture drainage textile geotechnical material based on stress regulation and control and preparation method thereof 南通大学 2026-05-15 CN claimed
US-4303787-A Process for recovering cyclodextrins RIKAGAKU KENKYUSHO (JP) 1981-12-01 US claimed
US-4278688-A Prostaglandin analogues ONO PHARMACEUTICAL CO. (JP) 1981-07-14 US claimed
US-4272276-A CYCLODEXTRINS CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) 1981-06-09 US claimed
US-4269674-A ELECTROLYTIC CHLORINATION OF A TOLUENE-INCLUDED CATHRATE OBTAINED BY ADDING TOLUENE TO AN ELECTROLYTIC CELL HAVING A CARBON ANODE WITH CYCLODEXTRIN BONDED TO THE SURFACE; CHLORIDE ELECTROLYTE; EFFICIENCY; CATALYST SELECTIVITY KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1981-05-26 US claimed
US-4265779-A WATER INSOLUBLE HYDROCARBON, NONIONIC ETHOXYLATE, AND A COMPATIBILIZING AGENT THE PROCTER & GAMBLE COMPANY (US) 1981-05-05 US claimed
US-4252783-A TREATMENT WITH A PEROXY COMPOUND SYVA COMPANY (US) 1981-02-24 US claimed
EP-0017242-A1 A process for producing cyclodextrins SANRAKU-OCEAN CO., LTD. (JP) 1980-10-15 EP claimed
US-4121975-A CYCLODEXTRIN AND SALICYLATE SYVA COMPANY (US) 1978-10-24 US claimed
US-4054736-A OXYTOCICS, CONTRACEPTIVES, HYPOTENSIVE, ANTIULCER, ANTIASTHMA ONO PHARMACEUTICAL CO., LTD. (JA) 1977-10-18 US claimed
US-4020160-A METABOLIC PROCESSES, ANTIINFLAMMATORY, ANTICOAGULANTS, ANTI-FIBRINOLYSIS, AND ANTIBODY-ANTIGEN REACTIVE AMERICAN CYANAMID COMPANY (US) 1977-04-26 US claimed