SCHEMBL2498102

SCHEMBL2498102

CC1(C)OC(=O)C(OCc2ccc(F)c(F)c2)=C1c1ccc(S(C)(=O)=O)cc1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 18/20 0.68
PTGS1 P23219 12/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4575852 0.81 PTGS2 (1.00) PTGS2PTGS1
SCHEMBL29671475 0.81 PTGS2 (1.00) PTGS2PTGS1
SCHEMBL7624385 0.78 PTGS2 (0.82) PTGS2PTGS1
SCHEMBL6964255 0.77 PTGS2 (0.73) PTGS2PTGS1
SCHEMBL4213329 0.77 PTGS2 (0.85) PTGS2PTGS1
SCHEMBL5203543 0.76 PTGS2 (0.83) PTGS2PTGS1
SCHEMBL5204977 0.76 PTGS2 (0.74) PTGS2PTGS1
SCHEMBL5208636 0.76 PTGS2 (0.74) PTGS2PTGS1
SCHEMBL6957905 0.75 PTGS2 (0.73) PTGS2PTGS1
SCHEMBL6957455 0.75 PTGS2 (0.73) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8030018-B2 Method for measuring enzymatic activity in vivo by use of laser SONY CORPORATION (JP) 2011-10-04 US disclosed
US-20080299541-A1 METHOD AND APPARATUS FOR MEASURING ENZYMATIC ACTIVITY BY USE OF LASER SONY CORPORATION (JP) 2008-12-04 US disclosed
EP-1997425-A1 Method and apparatus for measuring enzymatic activity by use of laser Sony Corporation (JP) 2008-12-03 EP disclosed