Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.58 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28989283 | 1.00 | CTSC (0.58) | CTSCCTSKKCNH2 | |
| SCHEMBL25369429 | 1.00 | CTSC (0.58) | CTSCCTSKKCNH2 | |
| SCHEMBL29455307 | 0.95 | CTSC (0.53) | CTSCCTSKKCNH2 | |
| SCHEMBL28989371 | 0.93 | CTSC (0.49) | CTSCCTSKKCNH2 | |
| SCHEMBL28989376 | 0.93 | CTSC (0.49) | CTSCCTSKKCNH2 | |
| SCHEMBL28989374 | 0.93 | CTSC (0.49) | CTSCCTSKKCNH2 | |
| SCHEMBL30738864 | 0.93 | CTSC (0.52) | CTSCCTSKKCNH2 | |
| SCHEMBL25146472 | 0.92 | CTSC (0.55) | CTSCCTSKKCNH2 | |
| SCHEMBL28989310 | 0.92 | CTSC (0.55) | CTSCCTSKKCNH2 | |
| SCHEMBL28989313 | 0.92 | CTSC (0.55) | CTSCCTSKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062420-A1 | NOVEL DPP1 INHIBITORS AND USES THEREOF | INSMED INC (US) | 2026-03-05 | — | — | US | disclosed |
| US-20250188067-A1 | SALT AND CRYSTAL FORM OF DIPEPTIDYL PEPTIDASE INHIBITOR COMPOUND | HAISCO PHARMACEUTICALS PTE. LTD. (SG) | 2025-06-12 | — | — | US | disclosed |
| US-20250179060-A1 | PREPARATION METHOD OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | HAISCO PHARMACEUTICALS PTE. LTD. (SG) | 2025-06-05 | — | — | US | disclosed |
| EP-4561565-A2 | NOVEL DPP1 INHIBITORS AND USES THEREOF | Insmed Incorporated (US) | 2025-06-04 | — | — | EP | disclosed |
| EP-4484414-A1 | SALT AND CRYSTAL FORM OF DIPEPTIDYL PEPTIDASE INHIBITOR COMPOUND | Haisco Pharmaceuticals Pte. Ltd. (SG) | 2025-01-01 | — | — | EP | disclosed |
| EP-4484423-A1 | PREPARATION METHOD OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Haisco Pharmaceuticals Pte. Ltd. (SG) | 2025-01-01 | — | — | EP | disclosed |
| CN-118742547-A | Preparation method of nitrogen-containing heterocyclic compound | 西藏海思科制药有限公司 | 2024-10-01 | — | — | CN | disclosed |
| WO-2024193695-A1 | PHARMACEUTICAL COMPOSITION CONTAINING DIPEPTIDYL PEPTIDASE SMALL MOLECULE INHIBITOR | 西藏海思科制药有限公司 | 2024-09-26 | — | — | WO | disclosed |
| CN-118660873-A | Salts and crystalline forms of dipeptidyl peptidase inhibitor compounds | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| WO-2024026433-A2 | NOVEL DPP1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED (US) | 2024-02-01 | — | — | WO | disclosed |
| US-11807635-B2 | Nitrile derivative that acts as inhibitor of dipeptidyl peptidase 1 and use thereof | HAISCO PHARMACEUTICALS PTE. LTD. (SG) | 2023-11-07 | — | — | US | disclosed |
| WO-2023160542-A1 | SALT AND CRYSTAL FORM OF DIPEPTIDYL PEPTIDASE INHIBITOR COMPOUND | 四川海思科制药有限公司 | 2023-08-31 | — | — | WO | disclosed |
| WO-2023160541-A1 | PREPARATION METHOD OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | 四川海思科制药有限公司 | 2023-08-31 | — | — | WO | disclosed |
| CN-115996923-A | Nitrile derivative as dipeptidyl peptidase 1 inhibitor and application thereof | 四川海思科制药有限公司 | 2023-04-21 | — | — | CN | disclosed |
| US-20230121807-A1 | NITRILE DERIVATIVE THAT ACTS AS INHIBITOR OF DIPEPTIDYL PEPTIDASE 1 AND USE THEREOF | HAISCO PHARMACEUTICALS PTE. LTD (SG) | 2023-04-20 | — | — | US | disclosed |
| EP-4129989-A1 | NITRILE DERIVATIVE THAT ACTS AS INHIBITOR OF DIPEPTIDYL PEPTIDASE 1 AND USE THEREOF | Haisco Pharmaceuticals Pte. Ltd. (SG) | 2023-02-08 | — | — | EP | disclosed |
| WO-2022042591-A1 | NITRILE DERIVATIVE THAT ACTS AS INHIBITOR OF DIPEPTIDYL PEPTIDASE 1 AND USE THEREOF | 四川海思科制药有限公司 | 2022-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11807635-B2 | Nitrile derivative that acts as inhibitor of dipeptidyl peptidase 1 and use thereof | DPP4, DPP3, DPP9 | CTSC 4/4885CTSK 454/4885KCNH2 4526/4885 |
| US-20250179060-A1 | PREPARATION METHOD OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | NIT2, NAAA, NUDT21 | CTSC 3581/4885CTSK 2791/4885KCNH2 1593/4885 |
| US-20250188067-A1 | SALT AND CRYSTAL FORM OF DIPEPTIDYL PEPTIDASE INHIBITOR COMPOUND | DPP7, DPP4, DPP8 | CTSC 9/4885CTSK 613/4885KCNH2 2186/4885 |
| US-20260062420-A1 | NOVEL DPP1 INHIBITORS AND USES THEREOF | DPP4, DPP3, DPP7 | CTSC 7/4885CTSK 1272/4885KCNH2 2268/4885 |
| US-20230121807-A1 | NITRILE DERIVATIVE THAT ACTS AS INHIBITOR OF DIPEPTIDYL PEPTIDASE 1 AND USE THEREOF | DPP4, DPP3, DPP9 | CTSC 4/4885CTSK 454/4885KCNH2 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.