⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11715755 | 0.71 | LMNA (0.30) | — | |
| SCHEMBL7931265 | 0.69 | — | — | |
| SCHEMBL11859303 | 0.69 | — | — | |
| SCHEMBL10685767 | 0.66 | — | — | |
| SCHEMBL11325138 | 0.66 | — | — | |
| SCHEMBL11884169 | 0.64 | — | — | |
| SCHEMBL16737202 | 0.62 | — | — | |
| SCHEMBL5550677 | 0.62 | — | — | |
| SCHEMBL28871100 | 0.60 | — | — | |
| SCHEMBL9707456 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030497-B2 | Benzimidazole derivatives | NOVARTIS AG (CH) | 2011-10-04 | — | — | US | disclosed |
| US-20090170921-A1 | Benzimidazole derivatives | NOVARTIS AG (CH) | 2009-07-02 | — | — | US | disclosed |