Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.41 |
| ▸ | NAMPT | P43490 | 5/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24033839 | 0.79 | GPR119 (0.38) | KDM4EMAPTTHRBGPR119NAMPT | |
| SCHEMBL31186963 | 0.79 | GPR119 (0.38) | KDM4EMAPTTHRBGPR119NAMPT | |
| SCHEMBL31186962 | 0.79 | GPR119 (0.38) | KDM4EMAPTTHRBGPR119NAMPT | |
| SCHEMBL24982940 | 0.74 | KDM4E (0.47) | KDM4EMAPTTHRBGPR119PTPN2 | |
| SCHEMBL20618024 | 0.74 | HPGD (0.46) | KDM4EMAPTTHRBGPR119PTPN2 | |
| SCHEMBL29548956 | 0.74 | HPGD (0.48) | KDM4EMAPTTHRBGPR119NAMPT | |
| SCHEMBL1344048 | 0.73 | USP2 (0.50) | GPR119NAMPTHPGD | |
| SCHEMBL23901636 | 0.72 | MAPT (0.45) | KDM4EMAPTTHRBGPR119PTPN2 | |
| SCHEMBL20337418 | 0.72 | USP2 (0.43) | KDM4EMAPTTHRBGPR119NAMPT | |
| SCHEMBL24703802 | 0.72 | HPGD (0.43) | KDM4EMAPTTHRBGPR119NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129987-A1 | CRYSTAL FORM OF FREE ALKALI OF NITROGEN-CONTAINING AROMATIC DERIVATIVES | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2023-02-08 | — | — | EP | disclosed |