Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CTSA | P10619 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22366910 | 0.89 | NPSR1 (0.45) | MRGPRX4MAPTCYP1A2CYP2C19NPSR1 | |
| SCHEMBL30185174 | 0.89 | NPSR1 (0.45) | MRGPRX4MAPTCYP1A2CYP2C19NPSR1 | |
| SCHEMBL24985309 | 0.88 | NPSR1 (0.44) | MRGPRX4NPSR1PTGDR2CFTRAGPAT2 | |
| SCHEMBL24985506 | 0.87 | MRGPRX4 (0.43) | MRGPRX4MAPTCYP1A2CYP2C19NPSR1 | |
| SCHEMBL24987861 | 0.87 | NPSR1 (0.43) | MRGPRX4MAPTNPSR1PTGDR2CFTR | |
| SCHEMBL22366843 | 0.87 | NPSR1 (0.43) | MRGPRX4NPSR1MEN1ALDH1A1KMT2A | |
| SCHEMBL30185251 | 0.87 | NPSR1 (0.43) | MRGPRX4NPSR1MEN1ALDH1A1KMT2A | |
| SCHEMBL30185313 | 0.87 | NPSR1 (0.43) | MRGPRX4MAPTNPSR1PTGDR2CFTR | |
| SCHEMBL24985021 | 0.86 | NPSR1 (0.42) | MRGPRX4MAPTNPSR1PTGDR2CFTR | |
| SCHEMBL24985500 | 0.86 | MAPT (0.47) | MRGPRX4MAPTCYP1A2CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | DOW AGROSCIENCES LLC (US) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | PDXK, DPYD, DDT | MRGPRX4 1870/4885MAPT 3017/4885CYP1A2 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.