Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | KYNU | Q16719 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13731382 | 1.00 | OPRM1 (0.57) | OPRM1SLC22A1LMNAHIF1AKDM4E | |
| SCHEMBL13731381 | 1.00 | OPRM1 (0.57) | OPRM1SLC22A1LMNAHIF1AKDM4E | |
| SCHEMBL2501603 | 1.00 | OPRM1 (0.57) | OPRM1SLC22A1LMNAHIF1AKDM4E | |
| SCHEMBL2495279 | 0.88 | HIF1A (0.48) | OPRM1SLC22A1LMNAHIF1AKDM4E | |
| SCHEMBL2503017 | 0.88 | HIF1A (0.48) | OPRM1SLC22A1LMNAHIF1AKDM4E | |
| SCHEMBL13730273 | 0.86 | OPRM1 (0.56) | OPRM1SLC22A1LMNAHIF1AKDM4E | |
| SCHEMBL19305061 | 0.86 | OPRM1 (0.56) | OPRM1SLC22A1LMNAHIF1AKDM4E | |
| SCHEMBL2494839 | 0.85 | HIF1A (0.46) | OPRM1SLC22A1LMNAHIF1AKDM4E | |
| SCHEMBL2497747 | 0.85 | HIF1A (0.46) | OPRM1SLC22A1LMNAHIF1AKDM4E | |
| SCHEMBL27810362 | 0.85 | HIF1A (0.46) | OPRM1SLC22A1LMNAHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030354-B2 | 2-(5,5-Dimethylcyclopent-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; metabolic disorders such as type II diabetes | AMGEN INC. (US) | 2011-10-04 | — | — | US | disclosed |