Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29232132 | 0.99 | OPRL1 (0.43) | OPRL1ALDH1A1KDM4ETDP1HTR2C | |
| Hydrochloric Acid SCHEMBL30164172 | 0.99 | OPRL1 (0.43) | OPRL1ALDH1A1KDM4ETDP1HTR2C | |
| SCHEMBL24985404 | 0.86 | OPRL1 (0.44) | OPRL1ALDH1A1KDM4ETDP1HTR2C | |
| SCHEMBL24986786 | 0.85 | ALDH1A1 (0.53) | OPRL1ALDH1A1KDM4ETDP1HTR2C | |
| Hydrochloric Acid SCHEMBL29232426 | 0.85 | OPRL1 (0.43) | OPRL1ALDH1A1KDM4ETDP1HTR2C | |
| Hydrochloric Acid SCHEMBL30918509 | 0.84 | ALDH1A1 (0.52) | OPRL1ALDH1A1KDM4ETDP1HTR2C | |
| Hydrochloric Acid SCHEMBL29232344 | 0.84 | ALDH1A1 (0.52) | OPRL1ALDH1A1KDM4ETDP1HTR2C | |
| Hydrochloric Acid SCHEMBL29232549 | 0.81 | OPRL1 (0.41) | OPRL1ALDH1A1KDM4ETDP1HTR2C | |
| Hydrochloric Acid SCHEMBL30163875 | 0.80 | OPRL1 (0.42) | OPRL1ALDH1A1KDM4ETDP1HTR2C | |
| Hydrochloric Acid SCHEMBL29232318 | 0.80 | OPRL1 (0.42) | OPRL1ALDH1A1KDM4ETDP1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006893-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN, IN PARTICULAR NEUROPATHIC PAIN, AND/OR OTHER DISEASES OR DISORDERS THAT ARE ASSOCIATED WITH AT2R AND/OR AT2R MEDIATED SIGNALING | CONFO THERAPEUTICS N.V. (BE) | 2023-02-02 | — | — | WO | disclosed |