SCHEMBL24986

SCHEMBL24986

NC(=O)CC1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 4/20 0.50
ALOX5 P09917 3/20 0.50
HPGD P15428 1/20 0.50
KMT2A Q03164 1/20 0.50
SLC1A3 P43003 2/20 0.41
SLC1A2 P43004 2/20 0.41
SLC1A1 P43005 2/20 0.41
EPHX2 P34913 1/20 0.41
CYP2D6 P10635 1/20 0.41
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH4 P08319 1/20 0.39
ADH7 P40394 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20379771 1.00 EPHX1 (0.50) EPHX1ALOX5HPGDKMT2ASLC1A3
SCHEMBL29291474 1.00 EPHX1 (0.50) EPHX1ALOX5HPGDKMT2ASLC1A3
SCHEMBL1327157 1.00 EPHX1 (0.50) EPHX1ALOX5HPGDKMT2ASLC1A3
SCHEMBL29291470 1.00 EPHX1 (0.50) EPHX1ALOX5HPGDKMT2ASLC1A3
SCHEMBL8915603 0.97 EPHX1 (0.48) EPHX1ALOX5HPGDKMT2ASLC1A3
Water SCHEMBL28513313 0.97 EPHX1 (0.48) EPHX1ALOX5HPGDKMT2ASLC1A3
Hydrochloric Acid SCHEMBL6921995 0.97 EPHX1 (0.48) EPHX1ALOX5HPGDKMT2ASLC1A3
SCHEMBL302210 0.97
SCHEMBL303513 0.92
SCHEMBL6270171 0.88 ANPEP (0.44) EPHX1ALOX5HPGDKMT2ASLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1577 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11471462-B2 Compositions and methods for detecting and treating diabetes THE BROAD INSTITUTE, INC. (US) 2022-10-18 US claimed
EP-2344456-B1 NOVEL POTASSIUM CHANNEL BLOCKER JAPAN TOBACCO INC (JP) 2018-07-25 EP claimed
WO-2017024010-A1 3-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-1H-INDAZOLES AND THERAPEUTIC USES THEREOF SAMUMED, LLC. (US) 2017-02-09 WO claimed
EP-2334637-B1 NOVEL POTASSIUM CHANNEL BLOCKERS JAPAN TOBACCO INC (JP) 2017-01-04 EP claimed
EP-1906945-B1 HCV INHIBITORS VIROBAY INC (US) 2015-08-05 EP claimed
CN-102292323-B Aryl methyl benzoquinazolinone M1 receptor positive allosteric modulators MERCK SHARP & DOHME 2014-12-24 CN claimed
US-20140187532-A1 4-(AZACYCLOALKYL)BENZENE-1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS GALDERMA RESEARCH & DEVELOPMENT (FR) 2014-07-03 US claimed
EP-2430023-B1 AZACYCLIC SPIRODERIVATIVES AS HSL INHIBITORS HOFFMANN LA ROCHE (CH) 2013-12-11 EP claimed
EP-2430019-B1 COMPOUNDS WITH TWO FUSED BICYCLIC HETEROARYL MOIETIES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE JANSSEN PHARMACEUTICA NV (BE) 2013-09-18 EP claimed
EP-2571880-A1 PYRROLO [2, 3 - B]PYRAZINE - 7 - CARBOXAMIDE DERIVATIVES AND THEIR USE AS JAK AND SYK INHIBITORS F.HOFFMANN-LA ROCHE AG (CH) 2013-03-27 EP claimed
US-6376491-B1 BENZOFURAN DERIVATIVES FOR TREATMENT OR PREVENTION OF MYCOSIS IN MAMMALS BASILEA PHARMACEUTICA AG (CH) 2002-04-23 US claimed
WO-2002024646-A1 DELTA1-PYRROLINES USED AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2002-03-28 WO claimed
EP-1149094-A2 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS Basilea Pharmaceutica AG (CH) 2001-10-31 EP claimed
CN-1311796-A Peptide antiangiogenic agents ABBOTT LAB (US) 2001-09-05 CN claimed
EP-1078002-A1 PEPTIDE ANTIANGIOGENIC DRUGS ABBOTT LABORATORIES (US) 2001-02-28 EP claimed
WO-2000037464-A2 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS BASILEA PHARMACEUTICA AG (CH) 2000-06-29 WO claimed
WO-1999061476-A1 PEPTIDE ANTIANGIOGENIC DRUGS ABBOTT LABORATORIES (US) 1999-12-02 WO claimed
CN-86108626-A Phenylformic acid and benzoate derivatives with anti-inflammatory and pain palliation efficacy 1987-07-22 CN claimed
US-4000287-A HYPOTENSIVES, ANTIARRHYTHMIC CIBA-GEIGY CORPORATION (US) 1976-12-28 US claimed
US-3935247-A COBALT OR COPPER PHTHALOCYANINE CATALYST THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-01-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140187532-A1 4-(AZACYCLOALKYL)BENZENE-1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS TYR, DDT, TH EPHX1 216/4885ALOX5 898/4885HPGD 152/4885
US-11471462-B2 Compositions and methods for detecting and treating diabetes SLC2A2, SLC2A1, SLC5A2 EPHX1 2528/4885ALOX5 901/4885HPGD 1023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.