Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
| ▸ | SLC6A12 | P48065 | 4/20 | 0.42 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.42 |
| ▸ | SLC6A13 | Q9NSD5 | 4/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL302210 | 0.91 | — | — | |
| SCHEMBL29291470 | 0.88 | EPHX1 (0.50) | ALOX5EPHX1HPGDKMT2ASLC1A3 | |
| Hydrochloric Acid SCHEMBL27767977 | 0.88 | ALOX5 (0.46) | ALOX5EPHX1HPGDKMT2ASLC1A3 | |
| SCHEMBL1327157 | 0.88 | EPHX1 (0.50) | ALOX5EPHX1HPGDKMT2ASLC1A3 | |
| SCHEMBL20379771 | 0.88 | EPHX1 (0.50) | ALOX5EPHX1HPGDKMT2ASLC1A3 | |
| SCHEMBL29291474 | 0.88 | EPHX1 (0.50) | ALOX5EPHX1HPGDKMT2ASLC1A3 | |
| SCHEMBL24986 | 0.88 | EPHX1 (0.50) | ALOX5EPHX1HPGDKMT2ASLC1A3 | |
| SCHEMBL221946 | 0.88 | — | — | |
| SCHEMBL8915603 | 0.86 | EPHX1 (0.48) | ALOX5EPHX1HPGDKMT2ASLC1A3 | |
| Hydrochloric Acid SCHEMBL6921995 | 0.86 | EPHX1 (0.48) | ALOX5EPHX1HPGDKMT2ASLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606244-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | Abbott Laboratories (US) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004037769-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | ABBOTT LABORATORIES (US) | 2004-05-06 | — | — | WO | disclosed |