SCHEMBL24988433

SCHEMBL24988433

N#Cc1ccc2c(c1)c1ccccc1n2-c1ccc2c(c1)c1ccccc1n2-c1ccc2c(c1)c1ccccc1n2-c1cccc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
G6PD P11413 2/20 0.36
PTGER4 P35408 2/20 0.35
RPS6KB1 P23443 1/20 0.34
RARG P13631 1/20 0.34
TDP2 O95551 4/20 0.33
RORC P51449 1/20 0.33
ENPP3 O14638 1/20 0.33
NOTUM Q6P988 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
MAT2A P31153 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24987658 1.00 KDM4E (0.41) KDM4EATML3MBTL1G6PDPTGER4
SCHEMBL22907605 1.00 KDM4E (0.41) KDM4EATML3MBTL1G6PDPTGER4
SCHEMBL22907622 1.00 KDM4E (0.41) KDM4EATML3MBTL1G6PDPTGER4
SCHEMBL24986601 0.96 KDM4E (0.38) KDM4EATML3MBTL1G6PDPTGER4
SCHEMBL24987898 0.96 KDM4E (0.38) KDM4EATML3MBTL1G6PDPTGER4
SCHEMBL24985627 0.96 KDM4E (0.38) KDM4EATML3MBTL1G6PDPTGER4
SCHEMBL24987657 0.95 KDM4E (0.39) KDM4EATML3MBTL1G6PDPTGER4
SCHEMBL24987858 0.95 KDM4E (0.39) KDM4EATML3MBTL1G6PDPTGER4
SCHEMBL24987899 0.95 KDM4E (0.39) KDM4EATML3MBTL1G6PDPTGER4
SCHEMBL24985622 0.94 KDM4E (0.38) KDM4EATML3MBTL1G6PDPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230019868-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230019868-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT-EMITTING DEVICE CYP1A1, AOX1, ODC1 KDM4E 3300/4885ATM 3528/4885L3MBTL1 950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.