Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24988188 | 0.88 | MAPT (0.44) | MAPTTSHRMAPK1TP53CYP1A2 | |
| SCHEMBL31143752 | 0.82 | CNR1 (0.38) | ALDH1A1TAAR1 | |
| SCHEMBL25371172 | 0.79 | TAAR1 (0.54) | MAPTMAPK1TP53CYP1A2ALOX15 | |
| SCHEMBL26055709 | 0.79 | KDM4E (0.36) | MAPTTSHRMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL14612463 | 0.78 | CTSL (0.39) | MAPTMAPK1CYP1A2ALDH1A1LMNA | |
| SCHEMBL24988630 | 0.76 | TAAR1 (0.60) | TAAR1SIGMAR1 | |
| SCHEMBL24988629 | 0.76 | TAAR1 (0.60) | TAAR1SIGMAR1 | |
| SCHEMBL24988526 | 0.76 | TAAR1 (0.60) | TAAR1SIGMAR1 | |
| SCHEMBL31143688 | 0.74 | CTSL (0.32) | — | |
| Homarylamine SCHEMBL29412731 | 0.73 | TAAR1 (0.61) | TSHRMAPK1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156453-A1 | PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | CYBIN IRL LIMITED (IE) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023288013-A2 | NOVEL SHORT-ACTING PSYCHOACTIVE COMPOUNDS OF THE MDMA CLASS | MYDECINE INNOVATIONS GROUP INC. (US) | 2023-01-19 | — | — | WO | disclosed |