Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 18/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17494791 | 1.00 | FFAR1 (0.55) | FFAR1LMNAHIF1AKDM4E | |
| SCHEMBL19181046 | 1.00 | FFAR1 (0.55) | FFAR1LMNAHIF1AKDM4E | |
| SCHEMBL2497755 | 1.00 | FFAR1 (0.55) | FFAR1LMNAHIF1AKDM4E | |
| SCHEMBL2495219 | 0.94 | FFAR1 (0.60) | FFAR1LMNAHIF1A | |
| SCHEMBL2504420 | 0.94 | FFAR1 (0.60) | FFAR1LMNAHIF1A | |
| SCHEMBL15973410 | 0.94 | FFAR1 (0.60) | FFAR1LMNAHIF1A | |
| SCHEMBL22717197 | 0.94 | FFAR1 (0.60) | FFAR1LMNAHIF1A | |
| SCHEMBL19201873 | 0.85 | FFAR1 (0.45) | FFAR1 | |
| SCHEMBL17537791 | 0.85 | FFAR1 (0.45) | FFAR1 | |
| SCHEMBL15971969 | 0.79 | FFAR1 (0.49) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030354-B2 | 2-(5,5-Dimethylcyclopent-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; metabolic disorders such as type II diabetes | AMGEN INC. (US) | 2011-10-04 | — | — | US | disclosed |