Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17537791 | 1.00 | FFAR1 (0.45) | FFAR1SLC6A3OPRD1OPRK1SLC6A4 | |
| SCHEMBL17503182 | 0.95 | FFAR1 (0.49) | FFAR1 | |
| SCHEMBL15990271 | 0.95 | FFAR1 (0.49) | FFAR1 | |
| SCHEMBL19175526 | 0.95 | FFAR1 (0.49) | FFAR1 | |
| SCHEMBL29377553 | 0.95 | FFAR1 (0.49) | FFAR1 | |
| SCHEMBL15971969 | 0.95 | FFAR1 (0.49) | FFAR1 | |
| SCHEMBL15973334 | 0.95 | FFAR1 (0.49) | FFAR1 | |
| SCHEMBL20103364 | 0.95 | FFAR1 (0.49) | FFAR1 | |
| SCHEMBL2498875 | 0.85 | FFAR1 (0.55) | FFAR1 | |
| SCHEMBL2497755 | 0.85 | FFAR1 (0.55) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968193-B2 | Antidiabetic bicyclic compounds | MERCK SHARP & DOHME CORP. (US) | 2021-04-06 | — | — | US | disclosed |
| US-20170217918-A1 | ANTIDIABETIC BICYCLIC COMPOUNDS | MERCK SHARP & DOHME LLC | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968193-B2 | Antidiabetic bicyclic compounds | GPR119, GPR65, GLP1R | FFAR1 14/4885SLC6A3 3643/4885OPRD1 884/4885 |
| US-20170217918-A1 | ANTIDIABETIC BICYCLIC COMPOUNDS | GPR119, GLP1R, GPR65 | FFAR1 11/4885SLC6A3 3361/4885OPRD1 822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.