SCHEMBL24991506

SCHEMBL24991506

NCCCCNC(=O)CNC(=O)[C@@H](Cc1ccc(F)cc1)NC(=O)CNC(=O)[C@H](CCC=O)NC(=O)Cc1ccc2ccccc2c1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CHRNA1 P02708 5/20 0.51
▸ CHRNG P07510 5/20 0.51
▸ CHRNB1 P11230 5/20 0.51
▸ CHRND Q07001 5/20 0.51
▸ GRIA1 P42261 6/20 0.49
▸ OPRD1 P41143 1/20 0.42
▸ CHRNB2 P17787 1/20 0.42
▸ CHRNB4 P30926 1/20 0.42
▸ CHRNA3 P32297 1/20 0.42
▸ CHRNA4 P43681 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24991172 0.85 PSMB8 (0.47) GRIA1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL23750093 0.80 CHRNA1 (0.42) CHRNA1CHRNGCHRNB1CHRNDGRIA1
SCHEMBL16485165 0.74 CHRNA1 (0.54) CHRNA1CHRNGCHRNB1CHRNDGRIA1
SCHEMBL23750092 0.74 CHRNA1 (0.47) CHRNA1CHRNGCHRNB1CHRNDGRIA1
SCHEMBL12510278 0.74 NPY4R (0.49) —
SCHEMBL16485174 0.72 CHRNB2 (0.52) CHRNA1CHRNGCHRNB1CHRNDGRIA1
SCHEMBL24991021 0.71 IL23R (0.57) —
SCHEMBL30179134 0.70 GNPAT (0.52) CHRNA1CHRNGCHRNB1CHRNDOPRD1
SCHEMBL30179445 0.69 TFPI (0.48) —
SCHEMBL30179352 0.69 TFPI (0.48) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230040236-A1 Diamine-Linked Melanocortin Receptor-Specific Cyclic Peptides for Ocular Indications PALATIN TECHNOLOGIES, INC. (US) 2023-02-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230040236-A1 Diamine-Linked Melanocortin Receptor-Specific Cyclic Peptides for Ocular Indications MC1R, MC3R, MC5R CHRNA1 673/4885CHRNG 500/4885CHRNB1 481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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