SCHEMBL24991864

SCHEMBL24991864

C[C@H](NC(=O)[C@@](O)(Cc1ccc(-c2ccccc2)cc1)CP(=O)(O)[C@H](C)N)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 3/20 0.58
▸ ANPEP P15144 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9369122 0.79 MME (0.50) MMEANPEP
SCHEMBL1764418 0.73 MME (1.00) MMEANPEP
SCHEMBL29684736 0.73 MME (1.00) MMEANPEP
SCHEMBL4992398 0.73 MME (1.00) MMEANPEP
SCHEMBL12609398 0.73 MME (1.00) MMEANPEP
SCHEMBL20526397 0.73 MME (1.00) MMEANPEP
SCHEMBL4992386 0.73 MME (1.00) MMEANPEP
SCHEMBL28798173 0.69 MME (0.90) MMEANPEP
SCHEMBL24991322 0.68 ANPEP (0.76) MMEANPEP
SCHEMBL28798169 0.68 MME (0.50) MMEANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230041504-A1 METHOD FOR THE INDUSTRIAL PREPARATION OF THE DISODIUM SALT OF ((2S)-3-([1,1'-BIPHENYL]-4-YL)-2-((HYDROXY((1R)-1-(((1-(ISOBUTYRYLOXY)ETHOXY)CARBONYL)AMINO)ETHYL)PHOSPHORYL) METHYL)PROPANOYL)-L-ALANINE KOS THERAPEUTICS, INC. 2023-02-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230041504-A1 METHOD FOR THE INDUSTRIAL PREPARATION OF THE DISODIUM SALT OF ((2S)-3-([1,1'-BIPHENYL]-4-YL)-2-((HYDROXY((1R)-1-(((1-(ISOBUTYRYLOXY)ETHOXY)CARBONYL)AMINO)ETHYL)PHOSPHORYL) METHYL)PROPANOYL)-L-ALANINE CHAMP1, AADAT, PTMS MME 1021/4885ANPEP 191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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