Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 13/20 | 0.53 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
| ▸ | MAP4K1 | Q92918 | 4/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24992317 | 0.95 | PTK2 (0.49) | EGFRALKPTK2MAP4K1 | |
| SCHEMBL24992470 | 0.93 | EGFR (0.56) | EGFRALKIGF1RPTK2MAP4K1 | |
| SCHEMBL24992319 | 0.87 | EGFR (0.49) | EGFRALKIGF1RPTK2MAP4K1 | |
| SCHEMBL30014786 | 0.87 | EGFR (0.69) | EGFRPTK2MET | |
| SCHEMBL24993148 | 0.87 | EGFR (0.61) | EGFRALKIGF1RPTK2MAP4K1 | |
| SCHEMBL24992455 | 0.87 | EGFR (0.69) | EGFRPTK2MET | |
| SCHEMBL26380369 | 0.87 | EGFR (0.60) | EGFRALKIGF1RPTK2MAP4K1 | |
| SCHEMBL24992476 | 0.85 | EGFR (0.57) | EGFRALKIGF1RPTK2MET | |
| SCHEMBL24993084 | 0.83 | EGFR (0.53) | EGFRALKIGF1RPTK2MET | |
| SCHEMBL24993179 | 0.83 | EGFR (0.55) | EGFRPTK2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011610-A1 | BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京红云生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |