Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 13/20 | 0.61 |
| ▸ | MET | P08581 | 2/20 | 0.61 |
| ▸ | INSR | P06213 | 8/20 | 0.55 |
| ▸ | IGF1R | P08069 | 8/20 | 0.55 |
| ▸ | ALK | Q9UM73 | 8/20 | 0.55 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.52 |
| ▸ | PLK4 | O00444 | 1/20 | 0.52 |
| ▸ | STK25 | O00506 | 1/20 | 0.52 |
| ▸ | RIOK3 | O14730 | 1/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | CASK | O14936 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | GAK | O14976 | 1/20 | 0.52 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.52 |
| ▸ | MUSK | O15146 | 1/20 | 0.52 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27075983 | 0.94 | EGFR (0.58) | EGFRMETINSRIGF1RALK | |
| SCHEMBL30015267 | 0.94 | EGFR (0.58) | EGFRMETINSRIGF1RALK | |
| SCHEMBL24992306 | 0.94 | EGFR (0.54) | EGFRMETINSRIGF1RALK | |
| SCHEMBL30014786 | 0.93 | EGFR (0.69) | EGFRMETCHEK1AURKAJAK2 | |
| SCHEMBL24992455 | 0.93 | EGFR (0.69) | EGFRMETCHEK1AURKAJAK2 | |
| SCHEMBL24993153 | 0.91 | EGFR (0.61) | EGFRMETINSRIGF1RALK | |
| SCHEMBL24992476 | 0.91 | EGFR (0.57) | EGFRMETINSRIGF1RALK | |
| SCHEMBL24992286 | 0.90 | EGFR (0.75) | EGFRMETINSRIGF1RALK | |
| SCHEMBL24992488 | 0.89 | EGFR (0.53) | EGFRMETINSRIGF1RALK | |
| SCHEMBL24993179 | 0.88 | EGFR (0.55) | EGFRMETCHEK1AURKAJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011610-A1 | BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京红云生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |