Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.44 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.44 |
| ▸ | INSR | P06213 | 2/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.44 |
| ▸ | CCNK | O75909 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CCND3 | P30281 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 2/20 | 0.44 |
| ▸ | ULK1 | O75385 | 1/20 | 0.42 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24993662 | 0.89 | MAPK9 (0.48) | EGFRMAPK9MAPK10BRD4MAPK8 | |
| SCHEMBL24993669 | 0.85 | BRD4 (0.41) | EGFRBRD4 | |
| SCHEMBL24992472 | 0.83 | BRD4 (0.55) | EGFRMAPK9MAPK10BRD4ALK | |
| SCHEMBL24992458 | 0.82 | BRD4 (0.54) | EGFRBRD4ALK | |
| SCHEMBL24993090 | 0.82 | BRD4 (0.44) | EGFRMAPK9MAPK10BRD4MAPK8 | |
| SCHEMBL24992309 | 0.81 | BRD4 (0.65) | EGFRBRD4ALKCCNKCCNA2 | |
| SCHEMBL24993047 | 0.81 | ALK (0.70) | EGFRMAPK9MAPK10MAPK8LRRK2 | |
| SCHEMBL24992488 | 0.81 | EGFR (0.53) | EGFRBRD4INSRALKIGF1R | |
| SCHEMBL24993153 | 0.79 | EGFR (0.61) | EGFRMAPK9MAPK10MAPK8LRRK2 | |
| SCHEMBL30015267 | 0.77 | EGFR (0.58) | EGFRZAP70INSRALKIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011610-A1 | BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京红云生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |